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pentobarbital will lower the level or outcome of netupitant/palonosetron by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Steer clear of or Use Alternate Drug. Netupitant is mainly metabolized by CYP3A4; stay away from use in clients who are chronically working with a strong CYP3A4 inducerBarbiturates have quite a few benefits. They’re m